SCHEMBL9851942

SCHEMBL9851942

ClSc1ccc(Oc2ccc(SCl)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
TSHR P16473 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 1/20 0.41
MEN1 O00255 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
MAOA P21397 2/20 0.39
MAOB P27338 1/20 0.39
LTA4H P09960 4/20 0.38
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35
MAPT P10636 3/20 0.33
PARP15 Q460N3 1/20 0.33
PARP14 Q460N5 1/20 0.33
PARP10 Q53GL7 1/20 0.33
PARP16 Q8N5Y8 1/20 0.33
PARP11 Q9NR21 1/20 0.33
PARP4 Q9UKK3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18658762 0.86 LTA4H (0.39) ALDH1A1TSHRKMT2ATDP1CYP3A4
SCHEMBL11250295 0.80 NR1H2 (0.32) TSHRCYP3A4NR1H2MAPTRAB9A
SCHEMBL1713002 0.78 CA1 (0.58) ALDH1A1TSHRKMT2ATDP1CYP3A4
SCHEMBL6872172 0.78
Hydrochloric Acid SCHEMBL4115862 0.76 CA1 (0.55) ALDH1A1TSHRTDP1CYP3A4ESR1
SCHEMBL23657399 0.75 VEGFA (0.37) MAPT
SCHEMBL4116218 0.72 MAPT (0.42) ALDH1A1TSHRMAPT
SCHEMBL28984725 0.72
SCHEMBL16473648 0.71 CYP1A2 (0.32) ALDH1A1TDP1CYP3A4ESR1ESR2
SCHEMBL12346047 0.71 KMT2A (0.48) ALDH1A1TSHRKMT2ATDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0407583-A1 DERIVATIVES OF DICHLORANHYDRIDES OF ACYLAMIDOPHOSPHORIC ACIDS AND INSECTICIDAL, FUNGIDICIDAL AND HEMATOCIDAL PREPARATIONS BASED ON THEM KIEVSKY NAUCHNO-ISSLEDOVATELSKY INSTITUT EPIDEMIOLOGII I INFEKTSIONNYKH BOLEZNEI IMENI L.V. GROMASCHEVSKOGO (SU) 1991-01-16 EP disclosed
US-3974163-A VULCANIZATION INHIBITOR MONSANTO COMPANY (US) 1976-08-10 US disclosed