⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851942 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL11250295 | 0.76 | NR1H2 (0.32) | — | |
| SCHEMBL1713002 | 0.74 | CA1 (0.58) | — | |
| SCHEMBL7865191 | 0.69 | — | — | |
| SCHEMBL4116218 | 0.69 | MAPT (0.42) | — | |
| SCHEMBL28984725 | 0.69 | — | — | |
| SCHEMBL1701770 | 0.65 | — | — | |
| SCHEMBL23657357 | 0.64 | KCNA3 (0.37) | — | |
| SCHEMBL18782860 | 0.63 | — | — | |
| SCHEMBL1226566 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011001088-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |