SCHEMBL1713002

SCHEMBL1713002

COc1ccc(SCl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
CYP1A1 P04798 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP1B1 Q16678 1/20 0.48
ACHE P22303 1/20 0.48
TDP1 Q9NUW8 4/20 0.46
MAPK1 P28482 4/20 0.46
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4115862 0.97 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL482369 0.78 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL438406 0.78 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL9851942 0.78 ALDH1A1 (0.41) TDP1ALDH1A1MAPTRAB9ACYP3A4
1,4-Dimethoxybenzene SCHEMBL8489 0.76 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL11250295 0.76 NR1H2 (0.32) MAPK1MAPTNPSR1NPC1RAB9A
1,4-Dimethoxybenzene SCHEMBL21802643 0.76 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL11986269 0.76 CYP1A1 (0.75) CA1CA2CA7CA9CA12
SCHEMBL1145983 0.76 CYP1A1 (0.75) CA1CA2CA7CA9CA12
SCHEMBL6617808 0.76 CA1 (0.61) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3814331-B9 NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY ORSOBIO INC (US) 2023-08-09 EP disclosed
CN-111662887-B Styrene epoxidase from rhizobia and function thereof 中国科学院成都生物研究所 2023-07-25 CN disclosed
EP-3814331-B1 NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY ORSOBIO INC (US) 2023-06-14 EP disclosed
EP-3515880-B1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF ENCODED LIBRARIES HITGEN INC (CN) 2023-05-10 EP disclosed
EP-3978471-B1 NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION UNIV CHINA PHARMA (CN) 2023-02-22 EP disclosed
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
EP-3978471-A1 NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION China Pharmaceutical University (CN) 2022-04-06 EP disclosed
US-11292968-B2 Sulfenamides as flame retardants SONGWON INTERNATIONAL AG (CH) 2022-04-05 US disclosed
CN-110872384-B Flame retardant composition, use thereof and method for the production thereof 松原国际股份有限公司 2022-02-25 CN disclosed
CN-113880777-A Preparation method and application of quinazolinone derivatives containing disulfide structures 贵州大学 2022-01-04 CN disclosed
EP-0055925-B1 ALKYL N-ARYLSULFENYL-N-DIARYLOXY-PHOSPHINYLMETHYLGLYCINATES AND THEIR USE AS HERBICIDES MONSANTO COMPANY (US) 1985-01-30 EP disclosed
US-4395374-A HERBICIDES, PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1983-07-26 US disclosed
US-4351843-A LOWERING BLOOD GLUCOSE PFIZER INC. (US) 1982-09-28 US disclosed
EP-0055925-A2 Alkyl N-arylsulfenyl-N-diaryloxy-phosphinylmethylglycinates and their use as herbicides MONSANTO COMPANY (US) 1982-07-14 EP disclosed
US-4300943-A Ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-11-17 US disclosed
US-4282242-A HYPOGLYCEMIC AGENTS PFIZER INC. (US) 1981-08-04 US disclosed
US-4282246-A Antidiabetic furancarboxylic and thiphenecarboxylic acids PFIZER INC. (US) 1981-08-04 US disclosed
US-4252554-A Herbicidal ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-02-24 US disclosed
US-3980787-A DIURETIC AND ANTIHYPERTENSIVE AGENTS AMERICAN HOECHST CORPORATION (US) 1976-09-14 US disclosed
US-3954997-A MITICIDES, INSECTICIDES THE UPJOHN COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11292968-B2 Sulfenamides as flame retardants STS, TST, PFAS CA1 1227/4885CA2 2010/4885CA7 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.