Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 19/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851963 | 1.00 | IRAK4 (0.38) | IRAK4KCNH2IRAK1 | |
| SCHEMBL9851972 | 1.00 | IRAK4 (0.38) | IRAK4KCNH2IRAK1 | |
| SCHEMBL18084625 | 0.79 | IRAK4 (0.40) | IRAK4KCNH2 | |
| SCHEMBL21290423 | 0.79 | IRAK4 (0.40) | IRAK4KCNH2 | |
| SCHEMBL21507384 | 0.79 | IRAK4 (0.40) | IRAK4KCNH2 | |
| SCHEMBL10755802 | 0.76 | THRB (0.36) | IRAK4IRAK1 | |
| SCHEMBL9994585 | 0.74 | MGLL (0.41) | IRAK4IRAK1 | |
| SCHEMBL5215585 | 0.74 | LMNA (0.39) | IRAK4KCNH2 | |
| SCHEMBL9865626 | 0.74 | LMNA (0.39) | IRAK4KCNH2 | |
| SCHEMBL18009250 | 0.73 | HCAR2 (0.38) | IRAK4IRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438311-A2 | Di- and tripeptide renin inhibitors | MERCK & CO. INC. (US) | 1991-07-24 | — | — | EP | disclosed |