Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852001 | 1.00 | FAAH (0.36) | FAAHSRD5A1SRD5A2PER2MAPT | |
| SCHEMBL9852002 | 0.78 | MAPT (0.35) | PER2MAPT | |
| SCHEMBL9852000 | 0.78 | MAPT (0.35) | PER2MAPT | |
| SCHEMBL4082877 | 0.74 | CHRM2 (0.46) | SRD5A1SRD5A2PER2MAPTAR | |
| SCHEMBL16830251 | 0.72 | ALDH1A1 (0.35) | SRD5A1SRD5A2PER2MAPTMEN1 | |
| SCHEMBL9851985 | 0.71 | CYP3A4 (0.33) | MEN1KMT2A | |
| SCHEMBL9851987 | 0.71 | CYP3A4 (0.33) | MEN1KMT2A | |
| SCHEMBL8859113 | 0.70 | ACE (0.41) | MEN1KMT2A | |
| SCHEMBL15018763 | 0.70 | ACE (0.41) | MEN1KMT2A | |
| SCHEMBL10864432 | 0.69 | CYP3A4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438311-A2 | Di- and tripeptide renin inhibitors | MERCK & CO. INC. (US) | 1991-07-24 | — | — | EP | disclosed |