Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 3/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852000 | 1.00 | MAPT (0.35) | MAPTBRD4PER2PTGER4PTGER3 | |
| SCHEMBL9851999 | 0.78 | FAAH (0.36) | MAPTPER2 | |
| SCHEMBL9852001 | 0.78 | FAAH (0.36) | MAPTPER2 | |
| SCHEMBL4338414 | 0.76 | CHRM2 (0.47) | BRD4PER2 | |
| SCHEMBL19218077 | 0.73 | PDK2 (0.35) | BRD4PTGER4PTGER2 | |
| SCHEMBL26744978 | 0.73 | PER2 (0.41) | BRD4PER2PTGER4PTGER3PTGER2 | |
| SCHEMBL26744923 | 0.73 | PER2 (0.41) | BRD4PER2PTGER4PTGER3PTGER2 | |
| SCHEMBL1712652 | 0.72 | PDK2 (0.39) | BRD4PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL4353142 | 0.70 | BRD4 (0.32) | BRD4 | |
| SCHEMBL1712650 | 0.70 | PDK2 (0.39) | BRD4PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438311-A2 | Di- and tripeptide renin inhibitors | MERCK & CO. INC. (US) | 1991-07-24 | — | — | EP | disclosed |