Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852332 | 0.94 | LMNA (0.38) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8865296 | 0.90 | LMNA (0.35) | LMNAKDM4EALDH1A1ESR1PTGS1 | |
| SCHEMBL8865337 | 0.90 | KDM4E (0.33) | LMNAKDM4EESR1PTGS1PDE4A | |
| SCHEMBL9852179 | 0.87 | LMNA (0.35) | LMNAKDM4EALDH1A1GFERHSD17B10 | |
| SCHEMBL9852265 | 0.86 | RECQL (0.36) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8865797 | 0.86 | RECQL (0.36) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL9696790 | 0.80 | ELANE (0.37) | LMNAKDM4EALDH1A1GFERESR1 | |
| SCHEMBL9852407 | 0.80 | CACNA1C (0.35) | LMNAKDM4EESR1PTGS1PDE4A | |
| SCHEMBL9852079 | 0.79 | KDM4E (0.36) | LMNAKDM4EESR1PTGS1PDE4A | |
| SCHEMBL9852089 | 0.78 | KDM4E (0.36) | LMNAKDM4EESR1PTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |