Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852139 | 0.85 | ELANE (0.32) | ELANELIPE | |
| SCHEMBL9852332 | 0.82 | LMNA (0.38) | ELANEESR1PTGS1PDE4AKDM4E | |
| SCHEMBL8865797 | 0.81 | RECQL (0.36) | ELANEESR1PTGS1PDE4AKDM4E | |
| SCHEMBL9852265 | 0.81 | RECQL (0.36) | ELANEESR1PTGS1PDE4AKDM4E | |
| SCHEMBL21081301 | 0.80 | ESR1 (0.48) | ELANEESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL9852153 | 0.79 | ESR1 (0.34) | ELANEESR1PTGS1PDE4AHPGD | |
| SCHEMBL8865337 | 0.79 | KDM4E (0.33) | ELANEESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL9852063 | 0.78 | LMNA (0.38) | ELANEESR1PTGS1PDE4AKDM4E | |
| SCHEMBL8864875 | 0.77 | KDM4E (0.38) | ELANEESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL9852179 | 0.76 | LMNA (0.35) | ELANEESR1PTGS1PDE4AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |