Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024693 | 0.86 | MAPT (0.45) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1702555 | 0.84 | BCHE (0.40) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8636766 | 0.83 | MAPT (0.42) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5666502 | 0.80 | RELA (0.42) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11136842 | 0.78 | APP (0.38) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11136441 | 0.74 | RAB9A (0.42) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL10706362 | 0.71 | MEN1 (0.41) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL400024 | 0.71 | MAPT (0.47) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1702568 | 0.71 | RELA (0.49) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL132789 | 0.70 | ALDH1A1 (0.41) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450599-A1 | An electrophotographic photosensitive material | NEC CORPORATION (JP) | 1991-10-09 | — | — | EP | disclosed |