Urea

Urea

SCHEMBL9852663

C1CCC1.NC(N)=O.O=[PH](O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
ALDH1A1 P00352 1/20 0.46
OR51E2 Q9H255 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
EPHX1 P07099 1/20 0.33
ACHE P22303 1/20 0.33
F2 P00734 1/20 0.32
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL15390631 0.88
Urea SCHEMBL1411805 0.83
Cyclohexane SCHEMBL1698647 0.83 LMNA (0.67) LMNAALDH1A1OR51E2TDP1EPHX1
Cyclooctane SCHEMBL1841524 0.83 LMNA (0.67) LMNAALDH1A1OR51E2TDP1EPHX1
Cyclopentane SCHEMBL2745905 0.83
Cyclohexane SCHEMBL1841235 0.83 LMNA (0.67) LMNAALDH1A1OR51E2TDP1EPHX1
Cyclohexane SCHEMBL3125968 0.83 LMNA (0.67) LMNAALDH1A1OR51E2TDP1EPHX1
Cycloheptane SCHEMBL1834654 0.83 LMNA (0.67) LMNAALDH1A1OR51E2TDP1EPHX1
Urea SCHEMBL900201 0.83
Phosphonic Acid SCHEMBL18691438 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408297-A1 Scale inhibition WARWICK INTERNATIONAL GROUP LIMITED (GB) 1991-01-16 EP claimed