Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852739 | 0.88 | PHGDH (0.48) | ALDH1A1SMN1; SMN2HPGDAKR1C3HTT | |
| SCHEMBL2638479 | 0.79 | LMNA (0.39) | ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL10725098 | 0.67 | ALDH1A1 (0.42) | ALDH1A1HPGDRAB9AKMT2APOLB | |
| SCHEMBL22828312 | 0.66 | ALDH1A1 (0.54) | CHRNA7ALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL6762420 | 0.64 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL11336822 | 0.63 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNARAB9AKMT2A | |
| SCHEMBL23417770 | 0.63 | HPGD (0.51) | ALDH1A1HPGDRAB9AKMT2AMAPT | |
| SCHEMBL4130406 | 0.62 | ALDH1A1 (0.46) | ALDH1A1HSD11B1HPGDLMNAKMT2A | |
| SCHEMBL31387921 | 0.62 | HPGD (0.76) | CHRNA7ALDH1A1HPGDLMNAAKR1C3 | |
| SCHEMBL23721664 | 0.62 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |