Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852761 | 0.88 | CHRNA7 (0.44) | AKR1C3RAB9AALDH1A1HPGDHTT | |
| SCHEMBL2638479 | 0.78 | LMNA (0.39) | ALDH1A1KDM4E | |
| SCHEMBL7445245 | 0.70 | ALDH1A1 (0.57) | PHGDHAKR1C3ALDH1A1HPGDTSHR | |
| SCHEMBL6800724 | 0.69 | SMN1; SMN2 (0.46) | PHGDHAKR1C3NPC1ALDH1A1FKBP1A | |
| SCHEMBL6795518 | 0.66 | MAPT (0.57) | PHGDHAKR1C3RAB9AALDH1A1MGLL | |
| (4-Chlorophenyl)(Morpholino)Methanone SCHEMBL6937394 | 0.66 | PHGDH (1.00) | PHGDHAKR1C3L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6801153 | 0.65 | ALDH1A1 (0.49) | PHGDHAKR1C3ALDH1A1HPGDTSHR | |
| SCHEMBL10725098 | 0.64 | ALDH1A1 (0.42) | NPC1RAB9AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL28611988 | 0.63 | PHGDH (0.71) | PHGDHAKR1C3NPC1RAB9AL3MBTL1 | |
| SCHEMBL19423879 | 0.63 | PHGDH (0.71) | PHGDHAKR1C3L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |