Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327145 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL28915596 | 0.75 | BTK (0.38) | BTK | |
| SCHEMBL9382694 | 0.71 | — | — | |
| SCHEMBL7839416 | 0.69 | CTSC (0.31) | — | |
| SCHEMBL14736807 | 0.68 | CHRM2 (0.34) | — | |
| SCHEMBL14736393 | 0.68 | CHRM2 (0.34) | — | |
| SCHEMBL14736773 | 0.68 | CHRM2 (0.34) | — | |
| SCHEMBL20329780 | 0.66 | BTK (0.44) | BTK | |
| SCHEMBL7099487 | 0.65 | ALDH1A1 (0.47) | BTK | |
| SCHEMBL7240625 | 0.65 | ALDH1A1 (0.47) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459568-A2 | Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use | MERCK SHARP & DOHME LTD. (GB) | 1991-12-04 | — | — | EP | disclosed |