Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852833 | 0.77 | PDE10A (0.33) | KMT2AKDM4E | |
| SCHEMBL7011867 | 0.77 | KMT2A (0.50) | ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL8720788 | 0.71 | CYP1A2 (0.56) | NPSR1ALDH1A1KDM4E | |
| SCHEMBL28478763 | 0.70 | NPSR1 (0.50) | NPSR1ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7008162 | 0.70 | EDNRB (0.48) | NPSR1ALDH1A1GAATSHRKMT2A | |
| SCHEMBL10083615 | 0.68 | ALDH1A1 (0.43) | ALDH1A1GAATSHRKMT2A | |
| SCHEMBL13173070 | 0.67 | KMT2A (0.42) | ALDH1A1HPGDGAATSHRPKM | |
| SCHEMBL7104339 | 0.65 | DYRK1A (0.37) | ALDH1A1HPGDGAAPKMKDM4E | |
| SCHEMBL13173072 | 0.64 | TSHR (0.42) | ALDH1A1TSHRPKMKMT2AKDM4E | |
| SCHEMBL17979462 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |