Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487380 | 0.81 | AKR1C1 (0.47) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4637662 | 0.81 | AKR1C1 (0.47) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4637584 | 0.81 | AKR1C1 (0.47) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10414654 | 0.80 | CES2 (0.47) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL11021630 | 0.80 | MAPK1 (0.47) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL7806202 | 0.80 | HSD11B1 (0.46) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL14968340 | 0.79 | CYP3A4 (0.43) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL8014005 | 0.79 | CA1 (0.46) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| Ammonia Solution, Strong SCHEMBL6650400 | 0.79 | AKR1C1 (0.45) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5166279 | 0.77 | OPRM1 (0.51) | LMNATDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417785-A1 | Process for preparing optically active 3-phenylglycidic acid esters | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |