Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186125 | 0.85 | KMT2A (0.40) | KMT2ALMNAMAPTPARP10CCNC | |
| SCHEMBL9852805 | 0.83 | PARP10 (0.46) | KMT2ALMNAPARP10CCNCCDK8 | |
| SCHEMBL7020112 | 0.81 | ALDH1A1 (0.33) | P4HTMALDH1A1 | |
| SCHEMBL3819124 | 0.77 | NQO1 (0.50) | KMT2AMAPTPARP10NQO1NPC1 | |
| SCHEMBL9852815 | 0.76 | MAPT (0.46) | KMT2ALMNAMAPTPARP10PLA2G4B | |
| SCHEMBL9852804 | 0.75 | KDM4E (0.36) | KMT2ALMNAMAPTMEN1TDP1 | |
| SCHEMBL8785759 | 0.74 | KDM4E (0.43) | KMT2ALMNAMAPTCCNCCDK8 | |
| SCHEMBL7166940 | 0.74 | NQO1 (0.61) | KMT2ALMNAPARP10PLA2G4BNPSR1 | |
| SCHEMBL9840341 | 0.73 | ALDH1A1 (0.53) | KMT2ALMNAMAPTNPC1PLK1 | |
| SCHEMBL185429 | 0.72 | ALDH1A1 (0.40) | KMT2ALMNANPSR1NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |