Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020112 | 0.79 | ALDH1A1 (0.33) | KDM4EALDH1A1HSD17B10HCAR2GABRP | |
| SCHEMBL9852820 | 0.75 | KMT2A (0.40) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6157107 | 0.73 | LMNA (0.39) | KDM4EALDH1A1MAPTLMNAHDAC6 | |
| SCHEMBL16400491 | 0.72 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL9840341 | 0.71 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL3837299 | 0.70 | SLC13A5 (0.37) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL185429 | 0.70 | ALDH1A1 (0.40) | KDM4EALDH1A1HSD17B10RAB9ANNMT | |
| SCHEMBL10359434 | 0.69 | RARB (0.55) | KDM4EALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL9862013 | 0.69 | SSTR4 (0.41) | KDM4EALDH1A1RAB9AHCAR2LMNA | |
| SCHEMBL9852803 | 0.69 | APLNR (0.45) | KDM4EALDH1A1HSD17B10MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |