Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263177 | 0.84 | ALDH1A1 (0.62) | ALDH1A1ACHESMN1; SMN2OPRL1 | |
| SCHEMBL5752267 | 0.83 | OPRD1 (0.59) | SLC6A4ALDH1A1ACHESMN1; SMN2OPRD1 | |
| SCHEMBL11259596 | 0.83 | ALDH1A1 (0.65) | ALDH1A1ACHESMN1; SMN2OPRL1 | |
| SCHEMBL8996232 | 0.81 | KCNA5 (0.53) | KCNA5KCNH2 | |
| SCHEMBL11609010 | 0.80 | ALDH1A1 (0.67) | ALDH1A1ACHESMN1; SMN2OPRD1OPRL1 | |
| SCHEMBL3114045 | 0.80 | ALDH1A1 (0.67) | ALDH1A1ACHESMN1; SMN2OPRL1MEN1 | |
| SCHEMBL11612810 | 0.78 | OPRD1 (0.54) | SLC6A4ALDH1A1ACHEOPRD1OPRL1 | |
| SCHEMBL11611128 | 0.78 | ALDH1A1 (0.68) | ALDH1A1ACHESMN1; SMN2OPRD1 | |
| SCHEMBL3432555 | 0.75 | MEN1 (0.63) | SLC6A4ADRB2NCF1PLD1OPRD1 | |
| SCHEMBL13600073 | 0.74 | CHRM2 (0.53) | SLC6A4ADRB2NCF1PLD1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |