Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853000 | 0.92 | SMN1; SMN2 (0.58) | SMN1; SMN2HPGDTSHRHSD17B10PRMT5 | |
| SCHEMBL15355387 | 0.85 | PRMT5 (0.55) | SMN1; SMN2HPGDTSHRHSD17B10PRMT5 | |
| SCHEMBL30647004 | 0.85 | PRMT5 (0.55) | SMN1; SMN2HPGDTSHRHSD17B10PRMT5 | |
| SCHEMBL324836 | 0.82 | PRMT5 (0.55) | SMN1; SMN2HPGDTSHRHSD17B10PRMT5 | |
| SCHEMBL9527451 | 0.82 | PRMT5 (0.57) | SMN1; SMN2HPGDTSHRHSD17B10PRMT5 | |
| SCHEMBL30023801 | 0.82 | NOTUM (0.58) | SMN1; SMN2HPGDTSHRHSD17B10PRMT5 | |
| SCHEMBL4072403 | 0.81 | HPGD (0.70) | SMN1; SMN2HPGDTSHRHSD17B10HDAC3 | |
| SCHEMBL22032274 | 0.80 | PRMT5 (0.61) | SMN1; SMN2HPGDTSHRHSD17B10PRMT5 | |
| SCHEMBL16268868 | 0.80 | ALDH1A1 (0.64) | SMN1; SMN2HPGDTSHRPRMT5WDR77 | |
| SCHEMBL324228 | 0.79 | TMEM97 (0.67) | PRMT5WDR77MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |