Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 6/20 | 0.57 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023801 | 0.85 | NOTUM (0.58) | PRMT5WDR77NOTUMTMPRSS2HTR1A | |
| SCHEMBL9853000 | 0.84 | SMN1; SMN2 (0.58) | PRMT5WDR77NOTUMTMPRSS2HTR1A | |
| SCHEMBL16268868 | 0.83 | ALDH1A1 (0.64) | PRMT5WDR77NOTUMTMPRSS2HTR1A | |
| SCHEMBL22032274 | 0.83 | PRMT5 (0.61) | PRMT5WDR77NOTUMTMPRSS2HTR1A | |
| SCHEMBL15355387 | 0.83 | PRMT5 (0.55) | PRMT5WDR77NOTUMABHD6MEN1 | |
| SCHEMBL324836 | 0.83 | PRMT5 (0.55) | PRMT5WDR77NOTUMABHD6MEN1 | |
| SCHEMBL30647004 | 0.83 | PRMT5 (0.55) | PRMT5WDR77NOTUMABHD6MEN1 | |
| SCHEMBL9852991 | 0.82 | SMN1; SMN2 (0.62) | PRMT5WDR77NOTUMTMPRSS2HTR1A | |
| SCHEMBL3721168 | 0.81 | PRMT5 (0.56) | PRMT5WDR77NOTUMABHD6TSHR | |
| SCHEMBL29698165 | 0.81 | PRMT5 (0.59) | PRMT5WDR77NOTUMABHD6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382380-B1 | PYRIDINIUM NITRATE, ITS PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-4981860-A | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
| EP-0382380-A1 | Pyridinium Nitrate, its production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-16 | — | — | EP | disclosed |