Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910376 | 0.77 | HPGD (0.54) | HPGDKDM4EALDH1A1GAAMAPT | |
| SCHEMBL11788309 | 0.76 | SOAT1 (0.35) | — | |
| SCHEMBL6594119 | 0.72 | HPGD (0.52) | HPGDKDM4EALDH1A1GAAMAPT | |
| SCHEMBL3183413 | 0.71 | KCNH3 (0.42) | MAPT | |
| SCHEMBL11380059 | 0.70 | SOAT1 (0.34) | HPGDKDM4EALDH1A1GAAMAPT | |
| SCHEMBL11375532 | 0.66 | LOXL2 (0.37) | HPGDKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL251932 | 0.65 | AR (0.60) | HPGDKDM4ESGK1ARLMNA | |
| SCHEMBL11378554 | 0.65 | TSHR (0.35) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL21024625 | 0.65 | KDM4E (0.66) | HPGDKDM4EALDH1A1GAAMAPT | |
| SCHEMBL20372815 | 0.65 | HPGD (0.68) | HPGDKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419831-A2 | Substituted sulfonylaminoazoles | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |