Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297823 | 0.81 | AURKA (0.48) | HPGDKDM4EGAAALDH1A1MAPT | |
| SCHEMBL21024625 | 0.79 | KDM4E (0.66) | HPGDKDM4EGAAALDH1A1MAPT | |
| SCHEMBL10471864 | 0.78 | HTT (0.41) | HPGDKDM4EGAALMNA | |
| SCHEMBL1385951 | 0.78 | HPGD (0.41) | HPGDKDM4EGAAALDH1A1MAPT | |
| SCHEMBL9853173 | 0.77 | HPGD (0.46) | HPGDKDM4EGAAALDH1A1MAPT | |
| SCHEMBL21686901 | 0.76 | LMNA (0.42) | KDM4EALDH1A1LMNAAURKADHFR | |
| SCHEMBL20372839 | 0.75 | KDM4E (0.61) | HPGDKDM4EGAAALDH1A1MAPT | |
| SCHEMBL11469083 | 0.75 | GLO1 (0.69) | ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL21633585 | 0.74 | AURKA (0.47) | KDM4EALDH1A1MAPTLMNAAURKA | |
| SCHEMBL6862349 | 0.74 | GLO1 (0.67) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637678-A | COUPLING DIAZO COMPONENT TO COUPLING COMPONENT, AT LEAST ONE OF WHICH CONTAINS 2-ARYLSULFONYLAMINO-PYRIMIDINE GROUP | SANDOZ LTD. (CH) | 1997-06-10 | — | — | US | disclosed |
| US-5554736-A | LEATHER, PELTS; COLORFASTNESS | CLARIANT FINANCE (BVI) LIMITED (VG) | 1996-09-10 | — | — | US | disclosed |
| US-5514783-A | Azo dyes containing a 2-(arylsulphonylamino)-pyrimidine radical and metal complexes thereof | SANDOZ LTD. (CH) | 1996-05-07 | — | — | US | disclosed |
| US-5510483-A | LEATHER DYE | SANDOZ LTD. (CH) | 1996-04-23 | — | — | US | disclosed |
| US-5510483-A | LEATHER DYE | SANDOZ LTD. (CH) | 1996-04-23 | — | — | US | disclosed |