Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL8395156 | 0.83 | — | — | |
| Glycine SCHEMBL5569329 | 0.79 | — | — | |
| Glycine SCHEMBL20295 | 0.79 | — | — | |
| Glycine SCHEMBL8585762 | 0.79 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL6853447 | 0.79 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL8723413 | 0.79 | — | — | |
| Glycine SCHEMBL8095196 | 0.79 | — | — | |
| Glycine SCHEMBL6239942 | 0.79 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL21879657 | 0.79 | GLRA1 (0.83) | — | |
| SCHEMBL905246 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419264-A2 | Aminophosphinates and polymers thereof and their use in detergent compositions | Albright & Wilson Limited (GB) | 1991-03-27 | — | — | EP | disclosed |