Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL27790097 | 0.93 | GLRA1 (0.67) | — | |
| Glycine SCHEMBL13169653 | 0.88 | — | — | |
| Glycine SCHEMBL93765 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL30179260 | 0.88 | — | — | |
| Glycine SCHEMBL6163 | 0.88 | — | — | |
| Glycine SCHEMBL6675874 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL2116443 | 0.88 | — | — | |
| Glycine SCHEMBL391027 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL391786 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL3640989 | 0.88 | GLRA1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103012475-B | A kind of preparation method of glyphosate | SHANDONG WEIFANG RAINBOW CHEMICAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-101628878-A | N-hydroxymethylglycine phosphite, preparation thereof and application thereof | JIAN LI | 2010-01-20 | — | — | CN | claimed |
| CN-113402549-B | Preparation method of glyphosate raw medicine | 安徽东至广信农化有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-113402549-A | Preparation method of glyphosate technical | 安徽东至广信农化有限公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-208747977-U | A kind of equipment that glyphosate synthesis hydrolyzes in the process and recycles triethylamine | 湖北泰盛化工有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-108329349-A | A kind of glyphosate synthesis hydrolyzes and recycles in the process the device and method of triethylamine | 湖北泰盛化工有限公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-108017671-A | The method of phosphorous acid glycine synthesizing glyphosate | 李坚 | 2018-05-11 | — | — | CN | disclosed |
| CN-108017671-A | The method of phosphorous acid glycine synthesizing glyphosate | 李坚 | 2018-05-11 | — | — | CN | disclosed |
| CN-103012475-B | A kind of preparation method of glyphosate | SHANDONG WEIFANG RAINBOW CHEMICAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103012475-A | Preparation method of glyphosate | SHANDONG WEIFANG RAINBOW CHEM | 2013-04-03 | — | — | CN | disclosed |
| CN-101628878-A | N-hydroxymethylglycine phosphite, preparation thereof and application thereof | JIAN LI | 2010-01-20 | — | — | CN | disclosed |
| EP-0915131-A1 | Flame-retarded thermoplastic resin composition | Ajinomoto Co., Inc. (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-3987006-A | LITHIUM INITIATED, COUPLED POLYMER | PHILLIPS PETROLEUM COMPANY (US) | 1976-10-19 | — | — | US | disclosed |