Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL1443448 | 0.79 | GNAO1 (0.35) | GNAI3GNAO1GNAI1 | |
| SCHEMBL38663400 | 0.75 | — | — | |
| SCHEMBL28481306 | 0.73 | — | — | |
| SCHEMBL1101241 | 0.67 | GBA2 (0.32) | GNAI3GNAO1GNAI1 | |
| SCHEMBL809348 | 0.67 | PTGS1 (0.31) | — | |
| SCHEMBL7059359 | 0.65 | PTGS1 (0.34) | EBPSIGMAR1 | |
| SCHEMBL7059429 | 0.65 | PTGS1 (0.34) | EBPSIGMAR1 | |
| SCHEMBL10456038 | 0.65 | PTGS1 (0.34) | EBPSIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL7060655 | 0.65 | PTGS1 (0.34) | EBPSIGMAR1 | |
| SCHEMBL5552727 | 0.65 | PTGS1 (0.34) | EBPSIGMAR1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413300-A1 | Pyrido [3,4-b][1,4] benzoxazepines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4940704-A | Pyrido[3,4-b][1,4]benzoxazepines | HOECHST-ROUSSEL PHARMACEUTICAL INC. (US) | 1990-07-10 | — | — | US | disclosed |