Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936600 | 0.84 | HDAC3 (0.43) | TP53HDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL9853429 | 0.79 | NR1H2 (0.47) | TP53KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL9212981 | 0.79 | TP53 (0.58) | TP53KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8936730 | 0.79 | TP53 (0.53) | TP53KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL8936648 | 0.79 | TP53 (0.45) | TP53HDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL8936654 | 0.79 | TP53 (0.45) | TP53HDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL8936630 | 0.77 | TP53 (0.51) | TP53KMT2AMAPTLMNAMEN1 | |
| SCHEMBL9099785 | 0.77 | TP53 (0.56) | TP53KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL9101435 | 0.76 | TP53 (0.60) | TP53KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8936669 | 0.72 | TP53 (0.46) | TP53KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417534-A1 | Pyrido[2,3-b][1,4]benzoxazepin (and thiazepin)-6(5H)-ones and thiones and their use in the prevention or treatment of AIDS | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1991-03-20 | — | — | EP | disclosed |