Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853427 | 0.70 | TP53 (0.48) | TP53MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL8936624 | 0.70 | HDAC3 (0.40) | TP53MAPTLMNASMN1; SMN2POLB | |
| SCHEMBL8936630 | 0.66 | TP53 (0.51) | TP53MAPTLMNAKMT2APOLB | |
| SCHEMBL8936730 | 0.65 | TP53 (0.53) | TP53MAPTKMT2APOLBTHRB | |
| SCHEMBL9101435 | 0.64 | TP53 (0.60) | TP53MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL8936648 | 0.63 | TP53 (0.45) | TP53MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL8936654 | 0.63 | TP53 (0.45) | TP53MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL9212981 | 0.63 | TP53 (0.58) | TP53MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL8103304 | 0.62 | KMT2A (0.36) | KMT2A | |
| SCHEMBL9853429 | 0.62 | NR1H2 (0.47) | TP53MAPTLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417534-A1 | Pyrido[2,3-b][1,4]benzoxazepin (and thiazepin)-6(5H)-ones and thiones and their use in the prevention or treatment of AIDS | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1991-03-20 | — | — | EP | disclosed |