Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316276 | 0.85 | SMN1; SMN2 (0.49) | MAPTGAASMN1; SMN2KMT2AGFER | |
| SCHEMBL1339690 | 0.83 | GFER (0.64) | MAPTGAASMN1; SMN2KMT2AGFER | |
| SCHEMBL1339688 | 0.83 | GFER (0.64) | MAPTGAASMN1; SMN2KMT2AGFER | |
| SCHEMBL17697018 | 0.82 | MAPT (0.52) | MAPTGAASMN1; SMN2KMT2AGFER | |
| SCHEMBL1141828 | 0.79 | BLM (0.43) | MAPTGAAKMT2AGFERALDH1A1 | |
| SCHEMBL16089348 | 0.79 | BLM (0.43) | MAPTGAAKMT2AGFERALDH1A1 | |
| SCHEMBL6711422 | 0.79 | GSTA1 (0.51) | MAPTGAASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6711416 | 0.79 | GSTA1 (0.51) | MAPTGAASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL9853492 | 0.78 | SMN1; SMN2 (0.77) | MAPTSMN1; SMN2KMT2AGFERALDH1A1 | |
| SCHEMBL6740766 | 0.78 | ALDH1A1 (0.45) | MAPTGAASMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433526-A1 | Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular | Richter, Peter, Prof. Dr.sc.nat. (DE) | 1991-06-26 | — | — | EP | disclosed |