Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | S100B | P04271 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853515 | 0.94 | MEN1 (0.36) | MEN1KMT2AMAPTALOX15SMN1; SMN2 | |
| SCHEMBL9853506 | 0.90 | MAPT (0.37) | MEN1KMT2AMAPTALOX15SMN1; SMN2 | |
| SCHEMBL9853493 | 0.78 | MAPT (0.39) | MAPTALOX15LMNAALDH1A1HTT | |
| SCHEMBL9853536 | 0.70 | MAPT (0.39) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9853500 | 0.69 | RECQL (0.48) | KMT2AMAPTALOX15SMN1; SMN2LMNA | |
| SCHEMBL1569040 | 0.67 | ALOX15 (0.41) | MAPTALOX15ALDH1A1HTTS100B | |
| SCHEMBL27536792 | 0.67 | MAPT (0.40) | MAPTALOX15LMNAALDH1A1HTT | |
| SCHEMBL11224675 | 0.66 | ALOX15 (0.40) | MAPTALOX15LMNAALDH1A1HTT | |
| SCHEMBL9853532 | 0.66 | S100B (0.44) | MEN1KMT2AMAPTALOX15SMN1; SMN2 | |
| SCHEMBL23337438 | 0.66 | MAPT (0.55) | MAPTALOX15ALDH1A1HTTS100B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433526-A1 | Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular | Richter, Peter, Prof. Dr.sc.nat. (DE) | 1991-06-26 | — | — | EP | claimed |