Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853493 | 0.86 | MAPT (0.39) | S100BMAPTLMNAALDH1A1HTT | |
| SCHEMBL9853536 | 0.73 | MAPT (0.39) | MAPTLMNAALDH1A1HTTNPSR1 | |
| SCHEMBL9853522 | 0.73 | RECQL (0.44) | S100BMAPTLMNAALDH1A1HTT | |
| SCHEMBL21248077 | 0.73 | MAPT (0.48) | S100BMAPTLMNAALDH1A1HTT | |
| SCHEMBL9853500 | 0.72 | RECQL (0.48) | S100BMAPTLMNAALDH1A1TP53 | |
| SCHEMBL7072159 | 0.71 | MAPT (0.67) | MAPTLMNAALDH1A1HTTTP53 | |
| SCHEMBL11180916 | 0.70 | ALDH1A1 (0.47) | S100BMAPTLMNAALDH1A1HTT | |
| SCHEMBL1720708 | 0.70 | S100B (0.57) | S100BMAPTLMNAALDH1A1HTT | |
| SCHEMBL31000389 | 0.69 | RECQL (0.67) | S100BMAPTLMNAALDH1A1HTT | |
| SCHEMBL30484136 | 0.69 | RECQL (0.67) | S100BMAPTLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433526-A1 | Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular | Richter, Peter, Prof. Dr.sc.nat. (DE) | 1991-06-26 | — | — | EP | disclosed |