Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853500 | 0.80 | RECQL (0.48) | TP53SMN1; SMN2GAARECQLALOX15 | |
| SCHEMBL30484136 | 0.73 | RECQL (0.67) | SMN1; SMN2GAARECQLALOX15MAPT | |
| SCHEMBL31000389 | 0.73 | RECQL (0.67) | SMN1; SMN2GAARECQLALOX15MAPT | |
| SCHEMBL145366 | 0.73 | RECQL (0.67) | SMN1; SMN2GAARECQLALOX15MAPT | |
| SCHEMBL9853522 | 0.71 | RECQL (0.44) | SMN1; SMN2GAARECQLALOX15MAPT | |
| Hydrochloric Acid SCHEMBL27581315 | 0.71 | RECQL (0.65) | SMN1; SMN2GAARECQLALOX15MAPT | |
| Hydrazine SCHEMBL11821861 | 0.71 | RECQL (0.65) | SMN1; SMN2GAARECQLALOX15MAPT | |
| Acetamide SCHEMBL16335345 | 0.70 | RECQL (0.59) | SMN1; SMN2GAARECQLALOX15MAPT | |
| SCHEMBL9853525 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2GAARECQLALOX15MAPT | |
| SCHEMBL9853497 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2GAARECQLALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433526-A1 | Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular | Richter, Peter, Prof. Dr.sc.nat. (DE) | 1991-06-26 | — | — | EP | claimed |