Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853500 | 0.76 | RECQL (0.48) | RECQLSMN1; SMN2GFERKMT2AS100B | |
| SCHEMBL31000389 | 0.76 | RECQL (0.67) | RECQLSMN1; SMN2GFERKMT2AS100B | |
| SCHEMBL145366 | 0.76 | RECQL (0.67) | RECQLSMN1; SMN2GFERKMT2AS100B | |
| SCHEMBL30484136 | 0.76 | RECQL (0.67) | RECQLSMN1; SMN2GFERKMT2AS100B | |
| Hydrazine SCHEMBL11821861 | 0.74 | RECQL (0.65) | RECQLSMN1; SMN2GFERKMT2AS100B | |
| Hydrochloric Acid SCHEMBL27581315 | 0.74 | RECQL (0.65) | RECQLSMN1; SMN2GFERKMT2AS100B | |
| Acetamide SCHEMBL16335345 | 0.73 | RECQL (0.59) | RECQLSMN1; SMN2GFERKMT2AS100B | |
| SCHEMBL9853532 | 0.73 | S100B (0.44) | SMN1; SMN2KMT2AS100BMAPTPPARG | |
| SCHEMBL9853559 | 0.71 | TP53 (0.39) | RECQLSMN1; SMN2GFERKMT2AS100B | |
| SCHEMBL9853497 | 0.71 | SMN1; SMN2 (0.46) | RECQLSMN1; SMN2GFERKMT2AS100B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433526-A1 | Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular | Richter, Peter, Prof. Dr.sc.nat. (DE) | 1991-06-26 | — | — | EP | claimed |