Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851746 | 0.78 | PTGS2 (0.33) | DAOCES2CES1PTGS2PTGS1 | |
| SCHEMBL9853616 | 0.76 | ERCC1 (0.52) | ERCC1FEN1ERCC4DAOPOLB | |
| SCHEMBL24303335 | 0.72 | USP2 (0.36) | MAPTTDP1KDM4EPTGS2PTGS1 | |
| SCHEMBL12235612 | 0.72 | CYP1B1 (0.43) | POLBMAPTTSHRKMT2AKDM4E | |
| SCHEMBL9249960 | 0.69 | ERCC1 (0.41) | ERCC1FEN1ERCC4DAOPOLB | |
| SCHEMBL7709451 | 0.68 | POLB (0.65) | ERCC1FEN1ERCC4POLBMAPT | |
| SCHEMBL6655099 | 0.68 | ERCC1 (0.38) | ERCC1FEN1ERCC4POLBMAPT | |
| SCHEMBL3280286 | 0.68 | TDP2 (0.52) | ERCC1FEN1ERCC4DAOPOLB | |
| SCHEMBL6650190 | 0.68 | POLB (0.51) | ERCC1FEN1ERCC4POLBMAPT | |
| SCHEMBL1025411 | 0.68 | ERCC1 (0.62) | ERCC1FEN1ERCC4POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417445-A1 | Single pot process for making a fluoroanthranilic acid | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4954639-A | REACTING FLUOROPHTHALIC ACID COMPOUND WITH HYDROXYLAMINE OR SALT | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |