Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497028 | 0.85 | IGLV6-57 (0.51) | ESR1ESR2TDP1KMT2AMEN1 | |
| SCHEMBL9298221 | 0.79 | SRD5A2 (0.45) | SRD5A2TDP1KMT2AMEN1TP53 | |
| SCHEMBL9860015 | 0.79 | SRD5A2 (0.45) | SRD5A2TDP1KMT2AMEN1RAB9A | |
| SCHEMBL3720563 | 0.76 | ALDH1A1 (0.48) | ESR1ESR2TDP1KMT2ATP53 | |
| SCHEMBL14878288 | 0.74 | TDP1 (0.45) | ESR1ESR2TDP1KMT2AMEN1 | |
| SCHEMBL4101422 | 0.74 | LTA4H (0.54) | ESR1ESR2TDP1KMT2AMEN1 | |
| SCHEMBL30517904 | 0.74 | TDP1 (0.45) | ESR1ESR2TDP1KMT2AMEN1 | |
| SCHEMBL8329782 | 0.74 | SRD5A2 (0.58) | SRD5A2ESR1ESR2TDP1KMT2A | |
| SCHEMBL28468103 | 0.74 | SRD5A2 (0.53) | SRD5A2KMT2AMEN1SMN1; SMN2PPARA | |
| SCHEMBL27627961 | 0.73 | ESR1 (0.42) | ESR1ESR2TDP1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |