SCHEMBL9857539

SCHEMBL9857539

Cc1cc(O)ccc1C(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.68
KMT2A Q03164 4/20 0.68
USP2 O75604 1/20 0.68
GAA P10253 1/20 0.68
KEAP1 Q14145 1/20 0.68
NFE2L2 Q16236 1/20 0.68
RAB9A P51151 2/20 0.56
NPC1 O15118 2/20 0.56
ALDH1A1 P00352 4/20 0.54
HPGD P15428 3/20 0.54
LMNA P02545 2/20 0.54
HTT P42858 2/20 0.54
CYP1A2 P05177 1/20 0.54
PGR P06401 1/20 0.54
CYP2D6 P10635 1/20 0.54
SLC6A2 P23975 1/20 0.54
PDE4A P27815 1/20 0.54
MAPK1 P28482 1/20 0.54
CYP2C19 P33261 1/20 0.54
HRH1 P35367 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29963348 1.00 MEN1 (0.68) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL1758224 0.90 HTT (0.60) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL30355061 0.90 HTT (0.60) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL19133555 0.85 MEN1 (0.62) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL12337417 0.85 ALDH1A1 (0.61) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL25384753 0.84 MEN1 (0.50) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL764844 0.84 SMN1; SMN2 (0.50) MEN1KMT2AUSP2GAAKEAP1
Benzoic Acid SCHEMBL20898427 0.84 ESR1 (0.53) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL3467555 0.84 CASP3 (0.55) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL2518517 0.83 KDM4E (0.70) MEN1KMT2AUSP2GAAKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105658702-A Highly heat resistant polysilsesquioxane-based photosensitive resin composition LTC有限公司 2016-06-08 CN disclosed
EP-0426846-A1 FLUORINATED-AROMATIC SULFONIC ACID CATALYST, PROCESS FOR ITS PRODUCTION, AND ITS USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed
CN-1040332-A Fluorine-containing aromatic sulfonic acid catalyzer and method for making and purposes MITSUI PETROCHEMICAL IND (JP) 1990-03-14 CN disclosed
US-4329360-A Benzophenones and their use as fungicides GAF CORPORATION (US) 1982-05-11 US disclosed
US-3998855-A INSECTICIDES CIBA-GEIGY CORPORATION (US) 1976-12-21 US disclosed
US-3980617-A Anti-solar polymers, method of making the same and cosmetic compositions containing the same L'OREAL (FR) 1976-09-14 US disclosed