Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 14/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853966 | 0.81 | TAAR1 (0.61) | TAAR1SMN1; SMN2KDM4E | |
| SCHEMBL22360002 | 0.73 | CYP4F2 (0.53) | TAAR1SMN1; SMN2 | |
| SCHEMBL31414967 | 0.73 | TAAR1 (0.75) | TAAR1MEN1LMNATSHRKMT2A | |
| SCHEMBL10997900 | 0.70 | TAAR1 (0.64) | TAAR1LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL3749613 | 0.70 | TAAR1 (0.64) | TAAR1MEN1LMNATSHRKMT2A | |
| SCHEMBL11474531 | 0.69 | TBXAS1 (0.56) | TAAR1MAPK1SMN1; SMN2 | |
| SCHEMBL7417625 | 0.69 | TAAR1 (0.55) | TAAR1LMNAMAPK1 | |
| SCHEMBL9243 | 0.69 | TAAR1 (1.00) | TAAR1MEN1LMNATSHRKMT2A | |
| Hydrochloric Acid SCHEMBL10944343 | 0.68 | TAAR1 (0.54) | TAAR1LMNAMAPK1 | |
| SCHEMBL10719843 | 0.68 | TAAR1 (0.66) | TAAR1HTR2BLMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934293-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004537-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |