Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853966 | 0.82 | TAAR1 (0.61) | TAAR1RAB9ASMN1; SMN2HTR1ACA2 | |
| SCHEMBL11487887 | 0.80 | TAAR1 (0.48) | CYP4F2CYP4A11TAAR1ALDH1A1MAPT | |
| SCHEMBL10948045 | 0.79 | PPARA (0.57) | TAAR1ALDH1A1MAPTHTR1AHPGD | |
| SCHEMBL4081419 | 0.79 | ALDH1A1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11475112 | 0.78 | ALOX5 (0.51) | CYP4F2CYP4A11TAAR1SMN1; SMN2MAPT | |
| SCHEMBL11479935 | 0.77 | TTR (0.47) | TAAR1SMN1; SMN2ALDH1A1MAPTHTR1A | |
| SCHEMBL129801 | 0.77 | CYP4F2 (0.71) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31414967 | 0.77 | TAAR1 (0.75) | TAAR1SMN1; SMN2ALDH1A1MAPTHTR1A | |
| SCHEMBL9302971 | 0.77 | MAPT (0.60) | CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10858172 | 0.76 | HCRTR1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020167952-A1 | MAT2A INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-08-20 | — | — | WO | disclosed |