Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549972 | 0.90 | LMNA (0.73) | LMNAALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL11596560 | 0.88 | ATM (0.64) | ALDH1A1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL10624502 | 0.86 | ATM (0.67) | ALDH1A1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL4349236 | 0.86 | ATM (0.65) | LMNAALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL13297311 | 0.85 | LMNA (0.64) | LMNAALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL3866038 | 0.84 | ATM (0.78) | LMNAALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL10783506 | 0.83 | LMNA (0.61) | LMNAALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL11453670 | 0.83 | ATM (0.57) | ALDH1A1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL822173 | 0.82 | ALDH1A1 (0.67) | LMNAALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL30195107 | 0.82 | ALDH1A1 (0.67) | LMNAALDH1A1ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |