Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693783 | 0.92 | NAAA (0.38) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL9856902 | 0.91 | NAAA (0.44) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL9743211 | 0.89 | NAAA (0.47) | NAAADGKAALDH1A1MAPTMAPK1 | |
| SCHEMBL9620490 | 0.85 | NAAA (0.46) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL9745575 | 0.83 | NAAA (0.53) | NAAADGKAMAPTMAPK1NPSR1 | |
| SCHEMBL9744401 | 0.82 | NAAA (0.52) | NAAADGKAALDH1A1MAPTMAPK1 | |
| SCHEMBL11090336 | 0.81 | NAAA (0.39) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL9742799 | 0.81 | PRKCA (0.41) | NAAADGKAALDH1A1MAPTLMNA | |
| SCHEMBL9743191 | 0.81 | NAAA (0.41) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL9743328 | 0.79 | ALDH1A1 (0.41) | DGKAALDH1A1MAPTMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269042-B1 | PROCESS FOR PREPARING 2 PROPENYLIDENE-3 ETHYL GLUTARIC ACID DIESTERS | BASF Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | disclosed |