Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 14/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854247 | 0.96 | AGTR1 (0.42) | LMNASMN1; SMN2AGTR1AGTR2NR1H4 | |
| SCHEMBL8874537 | 0.81 | NR1H4 (0.42) | LMNASMN1; SMN2AGTR1AGTR2NR1H4 | |
| SCHEMBL9854356 | 0.80 | LTB4R2 (0.48) | AGTR1AGTR2TP53RXFP1 | |
| SCHEMBL8872918 | 0.80 | AGTR1 (0.42) | AGTR1AGTR2TP53KDM4ERXFP1 | |
| SCHEMBL8949943 | 0.77 | OXTR (0.39) | NR1H4OXTRAVPR1A | |
| SCHEMBL8872195 | 0.77 | NR1H4 (0.38) | NR1H4OXTRAVPR1A | |
| SCHEMBL8872931 | 0.76 | ABL1 (0.37) | NR1H4OXTRAVPR1A | |
| SCHEMBL8872980 | 0.76 | OXTR (0.39) | NR1H4OXTRAVPR1A | |
| SCHEMBL8884587 | 0.75 | AGTR1 (0.49) | LMNAAGTR1AGTR2TP53KDM4E | |
| SCHEMBL8872708 | 0.75 | OXTR (0.37) | NR1H4OXTRAVPR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |