Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854346 | 0.96 | LMNA (0.47) | AGTR1AGTR2NR1H4LMNASMN1; SMN2 | |
| SCHEMBL8874537 | 0.85 | NR1H4 (0.42) | AGTR1AGTR2NR1H4LMNASMN1; SMN2 | |
| SCHEMBL9854356 | 0.82 | LTB4R2 (0.48) | AGTR1AGTR2TP53RXFP1 | |
| SCHEMBL8872918 | 0.82 | AGTR1 (0.42) | AGTR1AGTR2TP53KDM4ERXFP1 | |
| SCHEMBL8949943 | 0.81 | OXTR (0.39) | NR1H4OXTRAVPR1AABL1FFAR1 | |
| SCHEMBL8872195 | 0.80 | NR1H4 (0.38) | NR1H4OXTRAVPR1AABL1FFAR1 | |
| SCHEMBL8872931 | 0.80 | ABL1 (0.37) | NR1H4OXTRAVPR1AABL1FFAR1 | |
| SCHEMBL8872980 | 0.79 | OXTR (0.39) | NR1H4OXTRAVPR1AABL1ALDH1A1 | |
| SCHEMBL8872708 | 0.79 | OXTR (0.37) | NR1H4OXTRAVPR1AKDM4EABL1 | |
| SCHEMBL8873692 | 0.78 | OXTR (0.37) | NR1H4OXTRAVPR1AKDM4EABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |