1-Naphthol

1-Naphthol

SCHEMBL9854465

O=C(c1ccccc1)c1cc(O)cc(O)c1O.Oc1cccc2ccccc12

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
GAA P10253 2/20 0.54
KMT2A Q03164 2/20 0.54
USP2 O75604 1/20 0.54
KEAP1 Q14145 1/20 0.54
NFE2L2 Q16236 1/20 0.54
CYP1A2 P05177 2/20 0.49
BCL2 P10415 2/20 0.48
MCL1 Q07820 2/20 0.48
BAD Q92934 1/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 2/20 0.48
MAPK1 P28482 2/20 0.48
PGR P06401 1/20 0.48
CYP2D6 P10635 1/20 0.48
HPGD P15428 1/20 0.48
SLC6A2 P23975 1/20 0.48
PDE4A P27815 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8861243 0.86 MEN1 (0.70) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL8535254 0.80 FASN (0.66) MEN1GAAKMT2AUSP2KEAP1
2,4-Dihydroxybenzophenone SCHEMBL6059585 0.79 MEN1 (0.81) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL11057958 0.77 CDC25B (0.71) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL31393378 0.75 LDHA (0.70) MEN1KMT2ACYP1A2LMNAMAPK1
SCHEMBL9807419 0.75 LDHA (0.70) MEN1KMT2ACYP1A2LMNAMAPK1
1-Naphthol SCHEMBL4941930 0.74 CYP1A2 (0.68) MEN1GAAKMT2AUSP2CYP1A2
SCHEMBL14991108 0.74 FASN (0.61) MEN1GAAKMT2AUSP2KEAP1
1-Naphthol SCHEMBL7522683 0.74 CYP1A2 (0.81) MEN1GAAKMT2AUSP2CYP1A2
Phloroglucinol SCHEMBL9310647 0.73 BCL2 (0.57) MEN1GAAKMT2AUSP2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416762-A1 Cationic electrodeposition paint composition NISSAN MOTOR CO., LTD. (JP) 1991-03-13 EP claimed