Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873687 | 0.84 | AGTR1 (0.43) | AGTR1AGTR2ALDH1A1LMNATLR7 | |
| Ammonia Solution, Strong SCHEMBL8972320 | 0.83 | AGTR1 (0.60) | AGTR1AGTR2NOS1NOS2TLR7 | |
| SCHEMBL9260124 | 0.83 | AGTR1 (0.49) | AGTR1AGTR2GAAALDH1A1CHRM1 | |
| SCHEMBL9851478 | 0.82 | AGTR1 (0.52) | AGTR1AGTR2 | |
| Ammonia Solution, Strong SCHEMBL8972215 | 0.82 | AGTR1 (0.60) | AGTR1AGTR2NOS1NOS2TLR7 | |
| SCHEMBL9854484 | 0.81 | AGTR1 (0.49) | AGTR1AGTR2ALDH1A1HPGDLMNA | |
| SCHEMBL8972068 | 0.81 | AGTR1 (0.60) | AGTR1AGTR2LMNATP53POLB | |
| SCHEMBL8972044 | 0.80 | AGTR1 (0.65) | AGTR1AGTR2NOS1NOS2 | |
| SCHEMBL9874430 | 0.80 | AGTR1 (0.44) | AGTR1AGTR2ALDH1A1LMNATLR7 | |
| SCHEMBL9873722 | 0.80 | AGTR1 (0.44) | AGTR1AGTR2ALDH1A1LMNATLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |