Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.52 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854484 | 0.89 | AGTR1 (0.49) | AGTR1AGTR2BRD4H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | |
| SCHEMBL8972068 | 0.88 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL8972057 | 0.86 | AGTR1 (0.71) | AGTR1AGTR2PDE4APDE4BPDE4C | |
| SCHEMBL9854370 | 0.85 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9853674 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2BRD4H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16PDE4A | |
| SCHEMBL9853669 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2BRD4H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16PDE4A | |
| SCHEMBL29486817 | 0.85 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7622112 | 0.85 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL9851505 | 0.84 | AGTR1 (0.41) | AGTR1AGTR2BRD4 | |
| Ammonia Solution, Strong SCHEMBL9847776 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |