SCHEMBL9854576

SCHEMBL9854576

CCCCCO[SiH](CC)CC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.37
TSHR P16473 1/20 0.37
CA1 P00915 9/20 0.36
CA2 P00918 9/20 0.36
CA9 Q16790 9/20 0.36
CA12 O43570 4/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
LPAR3 Q9UBY5 6/20 0.34
LPAR2 Q9HBW0 5/20 0.34
LPAR1 Q92633 2/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
CA7 P43166 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA5B Q9Y2D0 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL863615 0.92 ADRB2 (0.41) THRBTSHRCA1CA2
SCHEMBL6298244 0.86 THRB (0.42) THRBTSHRCA1CA2CA9
SCHEMBL27848774 0.81 THRB (0.35) THRBTSHRCA1CA2CA9
SCHEMBL28686680 0.80 TSHR (0.32) THRBTSHRCA1CA2CA9
SCHEMBL25207287 0.80 THRB (0.32) THRBTSHRCA1CA2CA9
SCHEMBL3820999 0.79 DNM1 (0.38) TSHRCA1CA2CA9CA12
SCHEMBL28663646 0.79 THRB (0.40) THRBTSHRCA1CA2CA9
SCHEMBL6298300 0.78 TSHR (0.44) THRBTSHRMEN1KMT2A
SCHEMBL1608607 0.78 THRB (0.37) THRBTSHRCA1CA2CA9
SCHEMBL3820966 0.77 DNM1 (0.42) TSHRCA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101759818-A Process for producing solid catalyst component precursor for olefin polymerization SUMITOMO CHEMICAL CO 2010-06-30 CN disclosed
EP-0417346-A1 Process for producing solid catalyst for use in polymerization of olefins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-03-20 EP disclosed
EP-0206817-A1 Catalyst for producing olefin polymers and polymerization process using the catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-30 EP disclosed