Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 7/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68013 | 0.82 | TRPA1 (0.53) | TRPA1ATMTP53TDP1KDM4E | |
| SCHEMBL11464954 | 0.82 | ACHE (0.33) | TDP1ACHE | |
| SCHEMBL29457565 | 0.82 | TRPA1 (0.53) | TRPA1ATMTP53TDP1KDM4E | |
| SCHEMBL7990103 | 0.76 | — | — | |
| Hydroquinone SCHEMBL10426480 | 0.73 | ACHE (0.56) | TRPA1ATMKDM4EALDH1A1HTT | |
| SCHEMBL30388902 | 0.71 | TRPA1 (0.57) | TRPA1ATMTP53TDP1KDM4E | |
| SCHEMBL573212 | 0.71 | AR (0.47) | TRPA1ATMTP53TDP1KDM4E | |
| SCHEMBL394867 | 0.71 | CYP1A2 (0.35) | TRPA1ATMACHE | |
| SCHEMBL207038 | 0.71 | TRPA1 (0.57) | TRPA1ATMTP53TDP1KDM4E | |
| Acetic Acid SCHEMBL7711008 | 0.69 | CSNK2A1 (0.44) | TRPA1ATMTDP1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143956-A | 3,5-disubstituted and 3,4,5-trisubstituted 2-isoxazolines and isoxazoles, process for preparing same and their use as medicaments | HOECHST AG (DE) | 1997-02-26 | — | — | CN | claimed |
| EP-0412851-A2 | Photosensitive member and multi-color image forming method | CANON KABUSHIKI KAISHA (JP) | 1991-02-13 | — | — | EP | disclosed |
| EP-0363790-A2 | Image forming method and image forming medium | CANON KABUSHIKI KAISHA (JP) | 1990-04-18 | — | — | EP | disclosed |