Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910812 | 0.85 | NOTUM (0.59) | NOTUMKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL20905239 | 0.81 | NOTUM (0.40) | NOTUMALDH1A1IMPDH2 | |
| SCHEMBL31668328 | 0.80 | L3MBTL1 (0.55) | NOTUMKMT2AALDH1A1IMPDH2POLB | |
| SCHEMBL8685355 | 0.80 | L3MBTL1 (0.55) | NOTUMKMT2AALDH1A1IMPDH2POLB | |
| SCHEMBL1760744 | 0.79 | MEN1 (0.43) | NOTUMKMT2AMEN1ALDH1A1IMPDH2 | |
| SCHEMBL870631 | 0.78 | KMT2A (0.59) | KMT2AMEN1ALDH1A1IMPDH2GAA | |
| SCHEMBL11573644 | 0.77 | NOTUM (0.67) | NOTUMALDH1A1POLBOPRM1OPRL1 | |
| SCHEMBL856105 | 0.77 | BCHE (0.40) | NOTUMKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15558730 | 0.77 | NOTUM (0.50) | NOTUMKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL15558727 | 0.77 | NOTUM (0.50) | NOTUMKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |