Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414552 | 0.92 | ASAH1 (0.44) | BCHEASAH1ALDH1A1S1PR1HTT | |
| SCHEMBL9854713 | 0.77 | NOTUM (0.61) | ERN1NOTUMALDH1A1MEN1KMT2A | |
| Butyramide SCHEMBL28013718 | 0.75 | NOTUM (0.37) | NOTUMPDCD1CD274ALDH1A1MEN1 | |
| SCHEMBL8688017 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL20905239 | 0.72 | NOTUM (0.40) | NOTUMALDH1A1 | |
| SCHEMBL8685355 | 0.71 | L3MBTL1 (0.55) | NOTUMPDCD1CD274ALDH1A1KMT2A | |
| SCHEMBL31668328 | 0.71 | L3MBTL1 (0.55) | NOTUMPDCD1CD274ALDH1A1KMT2A | |
| SCHEMBL8686727 | 0.70 | APP (0.40) | BCHENOTUMPDCD1CD274ALDH1A1 | |
| SCHEMBL1760744 | 0.70 | MEN1 (0.43) | BCHENOTUMALDH1A1MEN1KMT2A | |
| SCHEMBL29955958 | 0.69 | ALDH1A1 (0.43) | ALDH1A1MEN1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143271-B2 | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143271-B2 | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC. (US) | 2012-03-27 | — | — | US | disclosed |