Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.42 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996977 | 0.85 | ALDH1A1 (0.46) | PPARGPPARACA12CA1CA2 | |
| SCHEMBL8000451 | 0.81 | FAAH (0.42) | PPARGPPARACA1CA2CA9 | |
| SCHEMBL9191664 | 0.77 | KDM4E (0.46) | PPARGPPARAFDFT1 | |
| SCHEMBL5993854 | 0.77 | PPARA (0.82) | PPARGPPARA | |
| SCHEMBL28649134 | 0.77 | PPARA (0.82) | PPARGPPARA | |
| SCHEMBL7987900 | 0.76 | HPGD (0.67) | MAOB | |
| SCHEMBL7987897 | 0.76 | HPGD (0.67) | MAOB | |
| SCHEMBL8003801 | 0.76 | FFAR1 (0.56) | PPARGPPARAFFAR1 | |
| SCHEMBL5992773 | 0.76 | PPARA (0.67) | PPARGPPARAFFAR1 | |
| SCHEMBL6941013 | 0.76 | CYP4F2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428423-A2 | Aryloxy alkyl benzenes, processes for their preparation and pharmaceutical compositions containing them | LIPHA S.A. (FR) | 1991-05-22 | — | — | EP | disclosed |