Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156180 | 0.92 | MAPK8 (0.35) | MAPK8MAPK9MAPK10 | |
| SCHEMBL28057563 | 0.91 | MAPK8 (0.39) | MAPK8MAPK9MAPK10 | |
| SCHEMBL18167357 | 0.84 | — | — | |
| SCHEMBL9565545 | 0.77 | CCNE1 (0.34) | — | |
| SCHEMBL9854792 | 0.74 | ALDH1A1 (0.46) | — | |
| SCHEMBL30703742 | 0.68 | QPCT (0.40) | — | |
| SCHEMBL2953146 | 0.68 | — | — | |
| SCHEMBL10600589 | 0.68 | ADRA1A (0.51) | — | |
| SCHEMBL2388908 | 0.68 | PAK1 (0.46) | MAPK8MAPK9MAPK10 | |
| SCHEMBL30865760 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433898-A2 | Analogs of oxetanyl purines and pyrimidines | ABBOTT LABORATORIES (US) | 1991-06-26 | — | — | EP | disclosed |